In honor to celebrate the 15th anniversary of Garfield, CBS aired the sixth season in 1993. For this season, the titles changed at the beginning. Instead of showing clips from only the first two seasons, which is what happened for the last three seasons, the titles included more clips from the fifth season, plus some from this season and one from a second season episode Health Feud, but still retaining a large amount of the original clips. However, the theme tune remained the same. Episodes 90–96 are available on the Garfield and Friends Volume 4 DVD set. Episodes 97–105 are available on Garfield and Friends Volume 5 DVD set.
Six months on, Ted (Jane) and Amanda (Chamoun) investigate a bizarre local murder and an exotic drug ring, whilst Amanda tangles with an old enemy and a new love, and Ted’s past stalks him and his family to Crimson Lake – with deadly consequences.